Whilst I agree the interiors in those Lexus you showed look nice (at least in comparison to the old IS), they don't have the same class as their BMW and Mercedes counterparts. Sure there's heaps of leather and wood stuck on everywhere in the photos you posted, but one look at the first photo (SC430) which happens to be the flagship, makes me think it looks as if the different sections in the centre console (ie. the air conditioning and radio) were made from different companies and just assembled together. In comparison, even the older BMWs from pre-2000 have had much more 'common look' in their dash in terms of all the displays looking the same, button layout, button style, etc...
I can see your point with the 'clinical' argument in regards to the German brands which seem to have moved towards the 'less wood' interiors, but you can always put the Elegance options in to get the wood back.
The ES picture you posted looks quite nice too though, but it still doesn't look seamlessly as one. Maybe this is because they want to allow people to modify their head units or something, but in that price bracket, I would prefer a more unified appearance. The transmission gates also look very out of date and old-fashioned in comparison to the new style look transmissions with tiptronic (bar the Jaguar- which has it's J-gate).
In terms of drive... I've only ever driven a 740 and an older model S class; and shotgun'd in 330, 645, 750, CL, S500, so I don't think I can really compare performance of those cars with the other models since I'm pretty sure the IS nor the new 3 series have half those features (eg. the suspension system which changes body height as you drive- or does it have it now?)... although like I said in another topic, the 740's 4.4L v8 did not feel as meaty as one would expect- at least not in comparison to a 540.